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Anxiety Disorders

Anxiety disorders include generalized anxiety disorder, panic disorder, obsessive‑compulsive disorder, social anxiety disorder, and post‑traumatic stress disorder. Persistent anxiety can become disabling and can require intervention with therapy, biofeedback, and relaxation techniques and/or the use of medications. Psychological manifestations of anxiety disorders can include fear and apprehension. Physical manifestations can include palpitations, tachycardia, and shortness of breath.

Sedative hypnotic anxiolytics: Benzodiazepines

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OTHER MEDICATIONS ● Diazepam ● Lorazepam ● Chlordiazepoxide ● Clorazepate ● Oxazepam ● Clonazepam


EXPECTED PhARmACOLOGICAL ACTION Benzodiazepines enhance the inhibitory effects of gamma-aminobutyric acid (GABA) in the CNS. Relief from anxiety occurs rapidly following administration.

ThERAPEUTIC USES Generalized anxiety disorder (GAD) and panic disorder

OTHER USES FOR BENZODIAZEPINES ● Trauma‑ and stressor‑related disorders: Acute

stress disorder (ASD) and post-traumatic stress disorder (PTSD)

● Hyperarousal manifestations of dissociative disorders ● Seizure disorders ● Insomnia ● Muscle spasm ● Alcohol withdrawal (for prevention and treatment of

acute manifestations) ● Induction of anesthesia ● Amnesic prior to surgery or procedures

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